Doctor’s Best
MSM Powder with OptiMSM
250 g
Three scoops (approximately 3 g) provide 3 g OptiMSM methylsulfonylmethane. The 250 g tub lists about 83 servings and no other ingredients.
Read ingredients & context ↗MSM.
4 product profiles across 4 brands. Compare the selected format, ingredients and evidence before choosing.
Search and filter this category ↗Small joint-symptom trials leave the size of benefit uncertain
Methylsulfonylmethane, usually called MSM, is an organosulfur compound sold alone or in joint blends. Some small trials have examined pain and physical function in knee osteoarthritis. Describing it as a sulfur source explains its chemistry, but does not establish that a person needs a supplement or that it repairs damaged cartilage.
Read the evidence limits and sources
The cited trial involved only 49 participants and reported improvements of uncertain clinical importance. Short, small studies cannot establish sustained benefit or long-term safety. Research on MSM alone also does not validate every joint blend or show that the listed branded formula has been tested.
Debbi et al. · MSM knee-osteoarthritis randomized trial (2011) ↗
Ingredient context reviewed 2026-10-26. General ingredient evidence does not verify the exact branded products below.
Explore msm products
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Jarrow Formulas
MSM - 1000mg Veggie Capsules
200 count — US label
Per 1 capsule: MethylSulfonylMethane (MSM) 1,000 mg.
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Life Extension
MSM — 1,000 mg
100 capsules; 33 three-capsule servings
The facts panel lists 3,000 mg methylsulfonylmethane (MSM) per three capsules, equivalent to 1,000 mg per capsule. The capsule ingredients include gelatin.
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Solgar
MSM — 1,000 mg
120 tablets; one-tablet serving
One tablet lists 1 g (1,000 mg) methylsulfonylmethane as OptiMSM. The pictured bottle contains 120 tablets.
Read ingredients & context ↗Products are arranged alphabetically by brand. Inclusion and ordering do not depend on an affiliate partnership. Check exact pack, seller and Indian delivery separately.