What’s inside this formula?
Jarrow Formulas’s SAMe - 400mg is listed here in the same collection. This article looks at the selected 30 count, 60 count — US label pack, then puts its ingredients into context.
Per 1 tablet: S-Adenosyl Methionine (from 800 mg of SAM e Tosylate Disulfate) 400 mg.
Check the original label ↗S-adenosylmethionine (SAMe) supplements use stabilized salts and sometimes enteric coatings. Compare active SAMe with the larger salt weight instead of treating both as additional ingredients.
The pack details above come from the manufacturer. Ingredient research below does not establish the effects of this exact product or independently verify its contents.
Read this formula on its own serving basis
The declared serving is 1 tablet. S-Adenosyl Methionine (from 800 mg of SAM e Tosylate Disulfate) 400 mg. These are label amounts, not an individual dosing recommendation. 30 count, 60 count — US label.
The comparison that matters
One tablet provides 400 mg SAMe from 800 mg tosylate-disulfate material. This is twice the active amount of the 200 mg version; compare active SAMe rather than salt weight. No independent test of the purchased bottle or clinical outcome for this complete formula was established in this label review.
Excipients, cautions and buying checks
Other-ingredient and allergen information: Microcrystalline cellulose, coating (hypromellose acetate succinate, stearic acid [vegetable source], triethyl citrate and riboflavin), glyceryl behenate, magnesium stearate (vegetable source), silicon dioxide, mannitol and sodium starch glycolate. No wheat, gluten, soybeans, dairy, egg, fish/shellfish, peanuts/tree nuts or sesame. The manufacturer excludes use in pregnancy, breastfeeding, Parkinson’s disease and bipolar/manic-depressive illness. SAMe can interact with antidepressants and other serotonergic medicines; do not self-treat depression. India delivery, authorised seller status, current stock and exact affiliate offers have not been verified.
Where might it be useful?
Identify the declared form
Compare the complete ingredient name, serving size and active amount. Brand terminology and carrier weights can differ between products.
Separate composition from outcomes
A clear panel can help compare products. Inclusion in this category is not an endorsement, a treatment recommendation or proof that supplementation is needed.
What the research can — and cannot — tell us
Trials of SAMe have limitations, and evidence is insufficient to establish dependable benefits across the conditions for which it is promoted. Ingredient research does not verify the exact branded product; long-term safety is uncertain.
What deserves your attention?
The manufacturer excludes use in pregnancy, breastfeeding, Parkinson’s disease and bipolar/manic-depressive illness. SAMe can interact with antidepressants and other serotonergic medicines; do not self-treat depression.
Suitability comes before strength
The manufacturer excludes use in pregnancy, breastfeeding, Parkinson’s disease and bipolar/manic-depressive illness. SAMe can interact with antidepressants and other serotonergic medicines; do not self-treat depression.
Dietary details for this product
Vegan The current manufacturer page explicitly marks this product vegan; this is a manufacturer claim, not independent certification.
A dietary label and an allergy assessment answer different questions. Check every ingredient, the capsule or softgel materials and the allergen statement on the pack you receive. If you take medicines, have a health condition, are pregnant or are choosing for a child, discuss the full formula with a qualified clinician.
Make the comparison meaningful.
- Match the exact version.Look for Jarrow Formulas · SAMe - 400mg and the 30 count, 60 count — US label pack. A similar name or bottle can contain a different strength, blend or serving.
- Compare like with like.Read the serving size alongside the active ingredient amount. Capsule count, compound weight and total blend weight can describe different things. Use the label notes above to see what matters for this formula.
- Check the seller and final cost.Review seller identity, expiry, batch details and any Indian import information. Compare the final delivered price only after matching the formula. Prices and stock are checked on the retailer’s site.
Keep the label beside the decision.
Open the complete product profile for its source, dietary notes and available shopping destination.
Is this an endorsement or a medical recommendation?
No. This is an editorial guide to a selected product and its ingredient context. We have not independently tested this bottle or established a clinical benefit for this exact formula. A product’s inclusion is not a recommendation that everyone should take it.
Does Proof & Price earn from shopping links?
Some product-profile links are paid links and are labelled. As an Amazon Associate we earn from qualifying purchases. Manufacturer source links are provided for checking the label. Read our affiliate disclosure.
Read, check, decide.
Product label reviewed 2026-11-01. Ingredient context reviewed 2026-11-01. This article has not received independent clinical review. Packaging and formulas can change; the current pack takes precedence.

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